This product is an aptamer which binds to the IgG Fc domain with an affinity of <100 nM.
Target Category | Antibody |
Target | IgG Fc domain |
Alternative Names | N/A |
Gene ID | N/A |
UniProt ID | N/A |
Target Overview | The fragment crystallizable region (Fc region) is the tail region of an antibody that interacts with cell surface receptors called Fc receptors and some proteins of the complement system. |
Chemical Modification | RNA |
Length | 20-40 nt |
Affinity (Kd) | <100 nM |
Binding Conditions/Buffer | 145 mM sodium chloride, 5.4 mM potassium chloride, 0.8 mM magnesium chloride, 1.8 mM calcium chloride, and 20 mM Tris HCl (pH 7.6) |
GC Content | 61 |
Molecular Weight | 7056.6 |
Extinction Coefficient | 226600 |
nmoles/OD260 | 3.861 |
These aptamers have been a useful addition to our labExcellentDelivery was prompt and the aptamers were well-packaged. We appreciated the detailed product information and felt confident in applying it to our experiments.
Robust performance and versatility within a range of experimental designsExcellentThis product has significantly improved our workflow and performance metrics. I honestly wasn't expecting such a dramatic change, but I'm glad I gave it a shot.
Shipping and packaging were perfect, and the product works as expectedExcellentI teach a biotechnity course at the university and this anti-IgG Fc domain aptamer is a great teaching tool. My students find it useful and reliable.
Easy to integrate into our workflowExcellentThis is the precise reagent we needed in our lab for IgG studies. It works well and consistently. I really appreciate the good service and prompt delivery.