Anti-IL1RN Aptamer SELEX Service(Cat#: CTApt-778)

This is an aptamer development services to screening aptamers binds to the IL1RN with an affinity of 1nM~1μM.

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Certificate of Analysis Lookup

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Summary

Specifications
Target Category Protein
Target IL1RN
Alternative Names DIRA; IRAP; IL1F3; IL1RA; MVCD4; IL-1RN; IL-1ra; IL-1ra3; ICIL-1RA
Gene ID 3557
UniProt ID P18510
Target Overview The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Several alternatively spliced transcript variants encoding distinct isoforms have been reported.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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