Anti-IL4 Aptamer SELEX Service(Cat#: CTApt-783)
This is an aptamer development services to screening aptamers binds to the IL4 with an affinity of 1nM~1μM.
Specific Inquiry 
Specifications
| Target Category |
Protein |
| Target |
IL4 |
| Alternative Names |
Interleukin 4; Lymphocyte Stimulatory Factor 1; IL-4; B_cell Stimulatory Factor 1; B Cell Growth Factor 1; Interleukin-4; Binetrakin; Pitrakinra; BCGF-1; BCGF1; BSF-1; BSF1; B-Cell Stimulatory Factor 1; Interleukin 4 Variant 2; MGC79402; IL4 |
| Gene ID |
3565 |
| UniProt ID |
P05112 |
| Target Overview |
The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. |
| Chemical Modification |
N/A |
| Type |
DNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
