Anti-Influenza virus B HA protein Aptamer (high affinity)(Cat#: CTMM-0124-TT47)

Name: Anti-Influenza virus B HA protein Aptamer (high affinity)
SKU: CTMM-0124-TT47
Rating: 5 (1 reviews)

This product is an aptamer which binds to the Influenza virus B HA protein with a high affinity of 200-1000 pM.

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Specifications

Target Category	Protein
Target	HA
Alternative Names	Hemagglutinin
Target Overview	Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induce an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore.
Type	RNA
Species Reactivity	Virus
Length	100-200 nt
Affinity (Kd)	200-1000 pM
Binding Conditions/Buffer	50 mM Tris-HCl, 25 mM NaCl, 5 mM MgCl₂, pH 7.5
GC Content	64.04%
Molecular Weight	35127.24 g/mole
nmoles/OD260	0.95

Anti-Influenza virus B HA protein Aptamer (high affinity)(Cat#: CTMM-0124-TT47)

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