Anti-ITGA4 Aptamer SELEX Service(Cat#: CTApt-855)
This is an aptamer development services to screening aptamers binds to the ITGA4 with an affinity of 1nM~1μM.
Specific Inquiry 
Specifications
| Target Category |
Protein |
| Target |
ITGA4 |
| Alternative Names |
Integrin Subunit Alpha 4; Alpha 4 Subunit Of VLA-4 Receptor; CD49 Antigen-Like Family Member D; VLA-4 Subunit Alpha; Integrin Alpha-IV; Integrin Alpha-4; CD49D 3 4; Integrin, Alpha 4 (Antigen CD49D, Alpha 4 Subunit Of VLA-4 Receptor); Very Late Activation Protein 4 Receptor, Alpha 4 Subunit; Antigen CD49D, Alpha-4 Subunit Of VLA-4 Receptor; 269C Wild Type; Antigen CD49D; CD49d Antigen; ITGA4; CD49d; IA4 |
| Gene ID |
3676 |
| UniProt ID |
P13612 |
| Target Overview |
The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants. |
| Chemical Modification |
N/A |
| Type |
DNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
