Anti-MMP9 Aptamer SELEX Service(Cat#: CTApt-797)

This is an aptamer development services to screening aptamers binds to the MMP9 with an affinity of 1nM~1μM.

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Specifications
Target Category Protein
Target MMP9
Alternative Names Matrix Metallopeptidase 9; Matrix Metalloproteinase 9 (Gelatinase B, 92kDa Gelatinase, 92kDa Type IV Collagenase); Matrix Metalloproteinase-9; EC 3.4.24.35; CLG4B; MMP-9; GELB; Matrix Metallopeptidase 9 (Gelatinase B, 92kDa Gelatinase, 92kDa Type IV Collagenase); 92 KDa Type IV Collagenase; Macrophage Gelatinase; Type V Collagenase; 92 KDa Gelatinase; Gelatinase B; EC 3.4.24; MANDP2; MMP9
Gene ID 4318
UniProt ID P14780
Target Overview Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other

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For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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