This product is an aptamer which binds to the Moenomycin A with an affinity of <400 nM.
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| Target Category | Small Organic |
| Target | Moenomycin A |
| Target Overview | Moenomycin A is the only known natural antibiotic that inhibits bacterial cell wall synthesis by binding to the transglycosylases that catalyze formation of the carbohydrate chains of peptidoglycan. |
| Chemical Modification | 2'-NH2-RNA |
| Length | 40-60 nt |
| Affinity (Kd) | <400 nM |
| Binding Conditions/Buffer | 20mM HEPES (pH 7.4), 150mM NaCl, and 5mM MgCl2. |
| GC Content | 0.7059 |
| Molecular Weight | 25776.83 g/mole |
| Extinction Coefficient | 514500 L/(mole·cm) |
| nmoles/OD260 | 1.94 |