This is an aptamer development services to screening aptamers binds to the MPO with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | MPO |
| Alternative Names | Myeloperoxidase; EC 1.11.1.7; EC 1.11.2.2; EC 1.11.1 |
| Gene ID | 4353 |
| UniProt ID | P05164 |
| Target Overview | Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of neutrophils. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |