Anti-MSH2 Aptamer SELEX Service(Cat#: CTApt-772)

Name: Anti-MSH2 Aptamer SELEX Service
SKU: CTApt-772
Rating: 5 (1 reviews)

This is an aptamer development services to screening aptamers binds to the MSH2 with an affinity of 1nM~1μM.

Certificate of Analysis Lookup

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Lot Number

Specifications

Target Category	Protein
Target	MSH2
Alternative Names	FCC1; COCA1; HNPCC; LCFS2; hMSH2; HNPCC1
Gene ID	4436
UniProt ID	P43246
Target Overview	This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.
Chemical Modification	N/A
Type	DNA
Length	20-80 nt
Affinity (Kd)	1nM~1μM
Binding Conditions/Buffer	PBS; buffer system with Serum; other