Anti-NAGS Aptamer SELEX Service(Cat#: CTApt-801)

This is an aptamer development services to screening aptamers binds to the NAGS with an affinity of 1nM~1μM.

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Summary

Specifications
Target Category Protein
Target NAGS
Alternative Names N-Acetylglutamate Synthase; N-Acetylglutamate Synthase, Mitochondrial; Amino-Acid Acetyltransferase; AGAS; ARGA; EC 2.3.1.1; NAGS; NAT7
Gene ID 162417
UniProt ID Q8N159
Target Overview The N-acetylglutamate synthase gene encodes a mitochondrial enzyme that catalyzes the formation of N-acetylglutamate (NAG) from glutamate and acetyl coenzyme-A. NAG is a cofactor of carbamyl phosphate synthetase I (CPSI), the first enzyme of the urea cycle in mammals. This gene may regulate ureagenesis by altering NAG availability and, thereby, CPSI activity. Deficiencies in N-acetylglutamate synthase have been associated with hyperammonemia.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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