This product is an aptamer which binds to the Hemin with an affinity of <50 nM.
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| Target Category | Protein |
| Target | Hemin |
| Chemical Modification | DNA |
| Length | 20-40 nt |
| Affinity (Kd) | <50 nM |
| Binding Conditions/Buffer | 20 mM Tris-AcOH (pH 8.0), 100 mM NaCl, 200 mM KCl, 5 mM MgCl2, 0.5% Triton X-100, and 5% DMSO. |
| GC Content | 0.6 |
| Molecular Weight | 6349.19 g/mole |
| Extinction Coefficient | 203600 L/(mole·cm) |
| nmoles/OD260 | 4.91 |
It's a powerful tool that has expanded the scope of our research significantlyExcellentOur lab has been using the anti-peroxidase DNAzyme aptamer for cell imaging applications, and we are thrilled with the results. The aptamer's ability to target specific peroxidase enzymes within live cells has allowed us to visualize and track changes in oxidative stress levels with high precision.
We'll undoubtedly continue to rely on it for future studiesExcellentI can't praise the anti-peroxidase DNAzyme aptamer enough. It's incredibly sensitive, and even at low enzyme concentrations, we can detect peroxidase activity accurately. The aptamer's specificity is unmatched, ensuring that we don't get any cross-reactivity with other enzymes. Our team has already published several papers using this aptamer.
I am extremely satisfied with its performanceExcellentIt has allowed us to study peroxidase dynamics in real-time, which was not feasible with traditional methods. This aptamer has been a real game-changer for our research.