Anti-Plasmodium falciparum HMGB1 Aptamer(Cat#: CTWZ-0124-WZ32)
This product is an aptamer which binds to Plasmodium falciparum HMGB1 with an affinity of 50-200 nM.
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Summary
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Specifications
| Target Category |
Protein |
| Target |
HMGB1 |
| Alternative Names |
High Mobility Group Box 1; SBP-1; HMG3; HMG1; High-Mobility Group (Nonhistone Chromosomal) Protein 1; Sulfoglucuronyl Carbohydrate Binding Protein; High Mobility Group Protein B1; High Mobility Group Protein 1; Amphoterin; HMG-1; High-Mobility Group Box 1; DKFZp686A04236; DKFZP686A04236 |
| Gene ID |
3146 |
| UniProt ID |
P09429 |
| Target Overview |
This gene encodes a protein that belongs to the High Mobility Group-box superfamily. The encoded non-histone, nuclear DNA-binding protein regulates transcription, and is involved in organization of DNA. This protein plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants that encode the same protein. |
| Type |
DNA |
| Species Reactivity |
Plasmodium falciparum |
| Length |
50-100 nt |
| Affinity (Kd) |
50-200 nM |
| Binding Conditions/Buffer |
100 mM NaCl, 1.5 mM KCl, 5 mM MgCl2, 6mM 2-Mercaptoethanol, 50 mM Tris HCl, pH 7.5 |
| GC Content |
51.14% |
| Molecular Weight |
26773.4 g/mole |
| nmoles/OD260 |
1.055 |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
