Anti-PRKAA2 Aptamer SELEX Service(Cat#: CTApt-2347)
This is an aptamer development services to screening aptamers binds to the PRKAA2 with an affinity of 1nM~1μM.
Specific Inquiry 
Specifications
| Target Category |
Protein |
| Target |
PRKAA2 |
| Alternative Names |
Protein Kinase AMP-Activated Catalytic Subunit Alpha 2; AMPK; 5'-AMP-Activated Protein Kinase Catalytic Subunit Alpha-2; Protein Kinase, AMP-Activated, Alpha 2 Catalytic Subunit; Hydroxymethylglutaryl-CoA Reductase Kinase; Acetyl-CoA Carboxylase Kinase; AMPK Subunit Alpha-2; ACACA Kinase; HMGCR Kinase; EC 2.7.11.1 ; AMPKa2; AMPK2; 5'-AMP-Activated Protein Kinase, Catalytic Alpha-2 Chain; AMP-Activated Protein Kinase Alpha-2 Subunit Variant 2; AMP-Activated Protein Kinase Alpha-2 Subunit Variant 3; AMPK-Alpha-2 Chain; AMPK Alpha 2; EC 2.7.11.27; EC 2.7.11.31; EC 2.7.11; PRKAA2; PRKAA |
| Gene ID |
5563 |
| UniProt ID |
P54646 |
| Target Overview |
The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia. |
| Chemical Modification |
N/A |
| Type |
DNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
