This is an aptamer development services to screening aptamers binds to the PYGB with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | PYGB |
| Alternative Names | GPBB |
| Gene ID | 5834 |
| UniProt ID | P11216 |
| Target Overview | The protein encoded by this gene is a glycogen phosphorylase found predominantly in the brain. The encoded protein forms homodimers which can associate into homotetramers, the enzymatically active form of glycogen phosphorylase. The activity of this enzyme is positively regulated by AMP and negatively regulated by ATP, ADP, and glucose-6-phosphate. This enzyme catalyzes the rate-determining step in glycogen degradation. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |