Anti-SERPINC1 Aptamer SELEX Service(Cat#: CTApt-2348)
This is an aptamer development services to screening aptamers binds to the SERPINC1 with an affinity of 1nM~1μM.
Specific Inquiry 
Specifications
| Target Category |
Protein |
| Target |
SERPINC1 |
| Alternative Names |
Serpin Family C Member 1; ATIII; Serine (Or Cysteine) Proteinase Inhibitor, Clade C (Antithrombin), Member 1; Serpin Peptidase Inhibitor, Clade C (Antithrombin), Member 1; Antithrombin-III; AT3; Coding Sequence Signal Peptide Antithrombin Part 1; Serpin Peptidase Inhibitor Clade C Member 1; Signal Peptide Antithrombin Part 1; Antithrombin (Aa 375-432); Antithrombin III Isoform; Antithrombin III; Serpin C1; ATIII-R2; ATIII-T1; ATIII-T2; SERPINC1; MGC2257; THPH7; AT3D |
| Gene ID |
462 |
| UniProt ID |
P01008 |
| Target Overview |
The protein encoded by this gene, antithrombin III, is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. Numerous mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency which constitutes a strong risk factor for thrombosis. |
| Chemical Modification |
N/A |
| Type |
DNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
