Anti-SMPD1 Aptamer SELEX Service(Cat#: CTApt-2350)

This is an aptamer development services to screening aptamers binds to the SMPD1 with an affinity of 1nM~1μM.

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Summary

Specifications
Target Category Protein
Target SMPD1
Alternative Names Sphingomyelin Phosphodiesterase 1; Acid Sphingomyelinase; ASM; Sphingomyelin Phosphodiesterase 1, Acid Lysosomal; Sphingomyelin Phosphodiesterase; EC 3.1.4.12; ASMASE; ASMase; SMPD1; NPD
Gene ID 6609
UniProt ID P17405
Target Overview The protein encoded by this gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB). Multiple transcript variants encoding different isoforms have been identified.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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