This is an aptamer development services to screening aptamers binds to the SMPD1 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | SMPD1 |
| Alternative Names | Sphingomyelin Phosphodiesterase 1; Acid Sphingomyelinase; ASM; Sphingomyelin Phosphodiesterase 1, Acid Lysosomal; Sphingomyelin Phosphodiesterase; EC 3.1.4.12; ASMASE; ASMase; SMPD1; NPD |
| Gene ID | 6609 |
| UniProt ID | P17405 |
| Target Overview | The protein encoded by this gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB). Multiple transcript variants encoding different isoforms have been identified. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |