Anti-SNCA Aptamer SELEX Service(Cat#: CTApt-2351)

This is an aptamer development services to screening aptamers binds to the SNCA with an affinity of 1nM~1μM.

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3’ Modification
 
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Summary

Specifications
Target Category Protein
Target SNCA
Alternative Names Synuclein Alpha; Alpha-Synuclein; NACP; Synuclein, Alpha (Non A4 Component Of Amyloid Precursor) ; PARK1; PD1; Parkinson Disease (Autosomal Dominant, Lewy Body) 4; Non A4 Component Of Amyloid Precursor; Non-A4 Component Of Amyloid Precursor; Non A-Beta Component Of AD Amyloid; Non-A Beta Component Of AD Amyloid; Truncated Alpha Synuclein; Synuclein Alpha-140; I+/--Synuclein; Α-Synuclein; PARK4; SNCA
Gene ID 6622
UniProt ID P37840
Target Overview Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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