Anti-TIMP2 Aptamer SELEX Service(Cat#: CTApt-844)

This is an aptamer development services to screening aptamers binds to the TIMP2 with an affinity of 1nM~1μM.

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Summary

Specifications
Target Category Protein
Target TIMP2
Alternative Names TIMP Metallopeptidase Inhibitor 2; CSC-21K; Tissue Inhibitor Of Metalloproteinases 2; Metalloproteinase Inhibitor 2; Tissue Inhibitor Of Metalloproteinase 2; Testicular Secretory Protein Li 57; TIMP-2; TIMP2; DDC8
Gene ID 7077
UniProt ID P16035
Target Overview This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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