This product is an aptamer which binds to the U87-EGFRvIII with an affinity of <20 nM.
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
| Target Category | Cell |
| Target | U87-EGFRvIII |
| Chemical Modification | DNA |
| Length | N/A |
| Affinity (Kd) | <20 nM |
| Binding Conditions/Buffer | 0.45 g of glucose, 10 mg yeast tRNA, 5 mg salmon sperm DNA, 0.1 g BSA and 0.5 ml of 1 M MgCl2 in 100 ml of 1X phosphate-buffered saline [PBS]. |
| GC Content | 0.3947 |
| Molecular Weight | 23560.41 g/mole |
| Extinction Coefficient | 734600 L/(mole·cm) |
| nmoles/OD260 | 1.36 |
High affinity makes it a valuable tool in our experimentsExcellentUsing it in our cell-based assay, the results were consistent and reproducible. Aptamer affinity has a significant impact on data reliability.
The anti-U87-EGFRvIII aptamer played a role in our drug screening assaysExcellentIts high affinity provided the sensitivity needed for the success of our experiments. The affinity of <20 nM ensured accurate and reproducible results in our screening assays.
Superior aptamer! Highly recommendedExcellentThe affinity of the anti-U87-EGFRvIII aptamer has proven to play an important role in our cell imaging studies. It is an essential reagent for our studies.