This product is an aptamer which binds to the U87-EGFRvIII with an affinity of <20 nM.
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| Target Category | Cell |
| Target | U87-EGFRvIII |
| Chemical Modification | DNA |
| Length | N/A |
| Affinity (Kd) | <20 nM |
| Binding Conditions/Buffer | 0.45 g of glucose, 10 mg yeast tRNA, 5 mg salmon sperm DNA, 0.1 g BSA and 0.5 ml of 1 M MgCl2 in 100 ml of 1X phosphate-buffered saline [PBS]. |
| GC Content | 0.4079 |
| Molecular Weight | 23496.35 g/mole |
| Extinction Coefficient | 730300 L/(mole·cm) |
| nmoles/OD260 | 1.37 |
I have great trust in its reliability and ease of use. Five starsExcellentAs a researcher new to aptamer technology, I found the product user-friendly. The detailed program provided is very helpful in setting up experiments.
This aptamer exceeded my expectationsExcellentThe enhanced signal-to-noise ratio allows for more accurate data collection. The anti-U87-EGFRvIII aptamer performed exceptionally well in my thesis experiments, providing accurate and reproducible results.
Impressed with the ease of customization of the aptamerExcellentThe flexibility it provides for experimental design is a significant advantage for researchers with diverse needs. I am currently applying it mainly for the accurate identification and characterization of target cell populations or for the detection of trace substances in samples.