This is an aptamer development services to screening aptamers binds to the VTCN1 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | VTCN1 |
| Alternative Names | V-Set Domain Containing T Cell Activation Inhibitor 1; B7-H4; B7H4; V-Set Domain-Containing T-Cell Activation Inhibitor 1; Immune Costimulatory Protein B7-H4; B7 Superfamily Member 1; B7 Family Member, H4; B7 Homolog 4; B7h.5; B7S1; T Cell Costimulatory Molecule B7x; T-Cell Costimulatory Molecule B7x; Protein B7S1; FLJ22418; PRO1291; VCTN1; VTCN1; B7X; B7x |
| Gene ID | 79679 |
| UniProt ID | Q7Z7D3 |
| Target Overview | This gene encodes a protein belonging to the B7 costimulatory protein family. Proteins in this family are present on the surface of antigen-presenting cells and interact with ligand bound to receptors on the surface of T cells. Studies have shown that high levels of the encoded protein has been correlated with tumor progression. A pseudogene of this gene is located on chromosome 20. Multiple transcript variants encoding different isoforms have been found for this gene. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |