Anti-XDH Aptamer SELEX Service(Cat#: CTApt-856)

This is an aptamer development services to screening aptamers binds to the XDH with an affinity of 1nM~1μM.

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Summary

Specifications
Target Category Protein
Target XDH
Alternative Names Xanthine Dehydrogenase; Xanthine Dehydrogenase/Oxidase; XOR; XO; Xanthine Oxidoreductase; Xanthene Dehydrogenase; EC 1.17.1.4; EC 1.7.2.2; XAN1; XDHA; XDH
Gene ID 7498
UniProt ID P47989
Target Overview Xanthine dehydrogenase belongs to the group of molybdenum-containing hydroxylases involved in the oxidative metabolism of purines. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Xanthine dehydrogenase can be converted to xanthine oxidase by reversible sulfhydryl oxidation or by irreversible proteolytic modification. Defects in xanthine dehydrogenase cause xanthinuria, may contribute to adult respiratory stress syndrome, and may potentiate influenza infection through an oxygen metabolite-dependent mechanism.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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