Mouse Anti-Human CD18 Monoclonal Antibody (CTJS-46)(Cat#: CTA-024)
This product is an unconjugated anti-Human CD18 Monoclonal antibody (CTJS-46) generated from the Mouse. The antibody can be used for WB; FC; IP.
Summary
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Specifications
| Clonality |
Monoclonal |
| Clone |
CTJS-46 |
| Host Animal |
Mouse |
| Isotype |
IgG1 |
| Immunogen |
Human peripheral blood mononuclear cells |
| Species Reactivity |
Human |
| Applications |
WB; FC; IP |
| Application Notes |
WB: 1:1000
FC: 8 µg/mL
IP: 1:50
The optimal working dilutions should be determined by the end user. |
| Specificity |
This antibody reacts with Human CD18. |
| Purity |
≥95% as determined by SDS-PAGE |
| Format |
Liquid |
| Size |
100 µg |
| Storage |
Store at 4° C short term. Avoid freeze/thaw cycles. After opening, prepare aliquots and store at -20°C. |
| Type |
Primary Antibody |
Target
| Target Name |
CD18 |
| Alternative Names |
Integrin Subunit Beta 2; Integrin, Beta 2 (Complement Component 3 Receptor 3 And 4 Subunit); Complement Component 3 Receptor 3 And 4 Subunit; Integrin, Beta 2 (Antigen CD18 (P95), Lymphocyte Function-Associated Antigen 1; Macrophage Antigen 1 (Mac-1) Beta Subunit); Cell Surface Adhesion Glycoprotein (LFA-1/CR3/P150, 959 Beta Subunit Precursor); Cell Surface Adhesion Glycoproteins LFA-1/CR3/P150, 95 Subunit Beta; Leukocyte-Associated Antigens CD18/11A, CD18/11B, CD18/11C; Leukocyte Cell Adhesion Molecule CD18; Complement Receptor C3 Beta-Subunit; Complement Receptor C3 Subunit Beta; Integrin Beta Chain, Beta 2; CD18 Antigen; LAD; CD18; MF17; MFI7; LCAMB; LFA-1; MAC-1 |
| Gene ID |
3689 |
| UniProt ID |
P05107 |
Information
| Introduction |
Integrin beta chain-2 (CD18) is an integrin beta chain protein that is encoded by the ITGB2 gene in humans. Upon binding with one of a number of alpha chains, CD18 is capable of forming multiple heterodimers, which play significant roles in cellular adhesion and cell surface signaling, as well as important roles in immune responses. CD18 also exists in soluble, ligand binding forms. Deficiencies in CD18 expression can lead to adhesion defects in circulating white blood cells in humans, reducing the immune system's ability to fight off foreign invaders. |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
