Home > Products > CD3 & GPNMB > Recombinant Anti-CD3 x Anti-GPNMB Bispecific Antibody (scFv-CH1/CL)

Recombinant Anti-CD3 x Anti-GPNMB Bispecific Antibody (scFv-CH1/CL)  (BSCC-088)

Recombinant Anti-CD3 x Anti-GPNMB Bispecific Antibody (scFv-CH1/CL) is designed to be expressed as two chains. One scFv from an anti-CD3 antibody variable domain is fused to CH1 and the other scFv from an anti-GPNMB antibody variable domain fused to CL, or vice versa. And the CH1 and CL domains are linked covalently via a natural disulfide bond. This BsAb can retarget T cells to tumor cells. It is designed for the research of Melanoma; Breast cancer therapy.

Specifications
Targets
CD3 & GPNMB
Type
scFv-based Bispecific Fragments
Species Reactivity
Human
Target 1
CD3
Host Animal 1
Mouse
Target 2
GPNMB
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Melanoma; Breast cancer
Targets
Target 1
CD3
Gene ID
UniProt ID
Alternative Names
CD3; CD3E; CD3e molecule; Cluster of differentiation 3; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3
Target 2
GPNMB
Gene ID
UniProt ID
Alternative Names
GPNMB; glycoprotein (transmembrane) nmb; ipd; Dchil; DC-HIL; transmembrane glycoprotein NMB; osteoactivin; iris pigment dispersion; dendritic cell-associated transmembrane protein; dendritic cell-associated heparin sulfate proteoglycan-dependent integrin ligand; Glycoprotein non-metastatic b
Our services and products are only for lab research, not for any diagnostic or therapeutic use.

Welcome! For price inquiries, we will get back to you as soon as possible.

To order, please email

INQUIRY
Online Inquiry
Please input "biolabs"(case insensitive) as verification code.
USA
45-1 Ramsey Road, Shirley, NY 11967, USA
Tel: 1-631-381-2994
Fax: 1-631-207-8356
Email:

Germany
Heidenkampsweg 58, 20097 Hamburg, Germany
Email:

UK
167-169 Great Portland Street, 5th Floor, London, W1W 5PE
Tel: 44-207-097-1828
Email:
Related products of "CD3 & GPNMB"
45-1 Ramsey Road, Shirley, NY 11967, USA 1-631-381-2994 1-631-207-8356
24x7 CUSTOMER SERVICE
Easy access to products and services you need from our library via
powerful searching tools
© 2007 - 2020 Creative-Biolabs All Rights Reserved.
Distributors
To view the contact information for a specific location,
select your country or region: