Recombinant Anti-CEA x Anti-GD2 Bispecific Antibody (scFv4-Ig) (FVTIG-138)

Recombinant Anti-CEA x Anti-GD2 Bispecific Antibody (scFv4-Ig) is an appended IgG format, which includes four scFv moieties at the N-termini of the constant regions. It is a bivalent homodimer, in which one anti-CEA scFv is fused to the CH1 domain of a heavy chain and another anti-GD2 scFv to the CL domain of a light chain, or vice versa. The resulting leads to 2+2 antigen-binding valency. This BsAb can bind two factors simultaneously. It is designed for the research of Neuroblastoma; Osteosarcoma; Melanoma; Solid tumors therapy.

Datasheet INQUIRY

Specifications

Targets

CEA & GD2

Type

Appended IgGs

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Neuroblastoma; Osteosarcoma; Melanoma; Solid tumors

Targets

Target 1

CEA

Gene ID

1048

UniProt ID

A0A024R0K5

Alternative Names

CEACAM5; carcinoembryonic antigen; carcinoembryonic antigen related cell adhesion molecule 5; CEA; CD66e; meconium antigen 100

Target 2

GD2

Alternative Names

Ganglioside GD2; GD2; Ganglioside; Disialoganglioside GD2

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-CEA x Anti-GD2 Bispecific Antibody (scFv4-Ig) (CAT#: FVTIG-138)

Specifications

Targets

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