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Recombinant Anti-CTLA4 x Anti-PD1 Bispecific Antibody (Single-chain Diabody)  (SCDB-146)

Recombinant Anti-CTLA4 x Anti-PD1 Bispecific Antibody (Single-chain Diabody) is designed to be expressed as one polypeptide chain with four variable domains from two parental antibodies. The middle linker is long enough to form scFv dimers between the two diabody chains. This BsAb can bind two factors simultaneously and enhance immune response. It is designed for the research of Tumors therapy.

Specifications

Targets
CTLA4 & PD1
Type
Single-chain Diabody
Species Reactivity
Human
Target 1
CTLA4
Host Animal 1
Mouse
Target 2
PD1
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Tumors

Targets

Target 1
CTLA4
Gene ID
UniProt ID
Alternative Names
CTLA4; cytotoxic T-lymphocyte-associated protein 4; CD; GSE; GRD4; ALPS5; CD152; CTLA-4; IDDM12; CELIAC3; cytotoxic T-lymphocyte protein 4; CD152 isoform; celiac disease 3; insulin-dependent diabetes mellitus 12; cytotoxic T-lymphocyte-associated serine esterase-4; cytotoxic T lymphocyte associated antigen 4 short spliced form; ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4
Target 2
PD1
Gene ID
UniProt ID
Alternative Names
PDCD1; programmed cell death 1; PD1; PD-1; CD279; SLEB2; hPD-1; hPD-l; hSLE1; programmed cell death protein 1; protein PD-1; systemic lupus erythematosus susceptibility 2

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