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Recombinant Anti-CTLA4 x Anti-PD1 Bispecific Antibody (scFv4-Ig) (CAT#: FVTIG-146)
Recombinant Anti-CTLA4 x Anti-PD1 Bispecific Antibody (scFv4-Ig) is an appended IgG format, which includes four scFv moieties at the N-termini of the constant regions. It is a bivalent homodimer, in which one anti-CTLA4 scFv is fused to the CH1 domain of a heavy chain and another anti-PD1 scFv to the CL domain of a light chain, or vice versa. The resulting leads to 2+2 antigen-binding valency. This BsAb can bind two factors simultaneously and enhance immune response. It is designed for the research of Tumors therapy.
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