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Recombinant Human Anti-DENV x Human Anti-CD64 Bispecific Antibody (scDiabody-Fc)  (CAT#: SCDBF-H316)

Recombinant Anti-DENV x Anti-CD64 Bispecific Antibody (scDiabody-Fc) is a fusion protein of two scDiabodies with an Fc region. In single-chain Diabodies, an additional connecting linker is introduced between chains of the anti-DENV/anti-CD64 diabody. The scDiabody with two specificities is further fused to the Fc domain to form BsAb with 2+2 antigen-binding valency. This BsAb can retarget neutrophils cells to dengue virus. It is designed for the research of Dengue virus infection therapy.
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Specifications

Targets
DENV & CD64
Type
Constant Domain-extended Bispecific Fragments
Species Reactivity
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Dengue virus infection

Targets

Target 1
DENV
Alternative Names
dengue virus; DENV; dengue fever; Flavivirus
Target 2
CD64
Gene ID
UniProt ID
Alternative Names
FCGR1A; Fc fragment of IgG receptor Ia; CD64; FCRI; CD64A; IGFR1; Cluster of Differentiation 64; FcγRI; FCGR1B; FCGR1C; immunoglobulin G Fc receptor high affinity I; Fc gamma RI
Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.
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