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Recombinant Anti-DENV x Anti-CD64 Bispecific Antibody (scFv-IgG) (CAT#: BSSG-147)
Recombinant Anti-DENV x Anti-CD64 Bispecific Antibody (scFv-IgG) is formed by an IgG and two scFv fragments. The scFvs from an anti-DENV antibody variable domain are respectively connected to the N terminus of the anti-CD64 IgG heavy chains or light chains to form scFv-(H)IgG or scFv-(L)IgG. It is a type of appended IgGs and has 2+2 antigen-binding valency. This BsAb can retarget neutrophils cells to dengue virus. It is designed for the research of Dengue virus infection therapy.
FCGR1A; Fc fragment of IgG receptor Ia; CD64; FCRI; CD64A; IGFR1; Cluster of Differentiation 64; FcγRI; FCGR1B; FCGR1C; immunoglobulin G Fc receptor high affinity I; Fc gamma RI
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