Recombinant Human Anti-IL1α x Human Anti-IL1β Bispecific Antibody (Diabody-Fc) (BSDBF-H342)

Recombinant Anti-IL1α x Anti-IL1β Bispecific Antibody (Diabody-Fc) is a fusion protein of two diabodies connected together by an Fc region. In a diabody, the two scFvs with short linkers are from anti-IL1α and anti-IL1β antibodies. The VH and VL domains form an inter-chain pairing. The diabody with different specificities is fused to the Fc fragment, which results in 2+2 antigen-binding valency and exerts Fc-mediated functions or just extends the half-life. This BsAb can block two proinﬂammatory cytokines simultaneously. It is designed for the research of Osteoarthritis (OA) therapy.

Datasheet INQUIRY

Specifications

Targets

IL1α & IL1β

Type

Constant Domain-extended Bispecific Fragments

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Osteoarthritis (OA)

Targets

Target 1

IL1α

Gene ID

3552

UniProt ID

P01583

Alternative Names

IL1; IL-1A; IL1F1; IL1-ALPHA; Interleukin 1 alpha; hematopoietin 1; IL1α

Target 2

IL1β

Gene ID

3553

UniProt ID

P01584

Alternative Names

IL-1; IL1F2; IL1-BETA; IL1β; Interleukin-1β; IL-1β

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

Online Inquiry

Customer Reviews and Q&As

There are currently no customer reviews or questions for Recombinant Human Anti-IL1α x Human Anti-IL1β Bispecific Antibody (Diabody-Fc) (BSDBF-H342). Click the button below to contact us or submit your feedback about this product.

Recombinant Human Anti-IL1α x Human Anti-IL1β Bispecific Antibody (Diabody-Fc) (CAT#: BSDBF-H342)

Specifications

Targets

Customer Reviews and Q&As