Name: Recombinant Anti-IL1α x Anti-IL1β Bispecific Antibody (F(ab')2-scFv2)
SKU: BABFV-177
Rating: 5 (1 reviews)

Recombinant Anti-IL1α x Anti-IL1β Bispecific Antibody (F(ab')2-scFv2) is designed to be expressed as two chains combined via a hinge region. The scFv of the anti-IL1α specificity is fused to the C terminus of the anti-IL1β Fab fragment, or vice versa. This format comprises four binding sites (two same scFv regions and two same Fab fragments), two for each antigen. This BsAb can block two proinﬂammatory cytokines simultaneously. It is designed for the research of Osteoarthritis (OA) therapy.

Datasheet INQUIRY

Specifications

Targets

IL1α & IL1β

Type

Fab-Fc Fusion Proteins

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Osteoarthritis (OA)

Targets

Target 1

IL1α

Gene ID

3552

UniProt ID

P01583

Alternative Names

IL1; IL-1A; IL1F1; IL1-ALPHA; Interleukin 1 alpha; hematopoietin 1; IL1α

Target 2

IL1β

Gene ID

3553

UniProt ID

P01584

Alternative Names

IL-1; IL1F2; IL1-BETA; IL1β; Interleukin-1β; IL-1β

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-IL1α x Anti-IL1β Bispecific Antibody (F(ab')2-scFv2) (CAT#: BABFV-177)

Specifications

Targets

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