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Recombinant Anti-IL1α x Anti-IL1β Bispecific Antibody (scFv-CH3) (CAT#: BSFC-177)
Recombinant Anti-IL1α x Anti-IL1β Bispecific Antibody (scFv-CH3) contains two chains. The anti-IL1α scFv is fused to the Knob-CH3 domain via a hinge region and the same as the anti-IL1β scFv to the Hole-CH3 domain, or vice versa. The KIH CH3 domains can facilitate to form a heterodimer and this bivalent binding leads to improvement in avidity. This BsAb can block two proinflammatory cytokines simultaneously. It is designed for the research of Osteoarthritis (OA) therapy.
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