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Recombinant Human Anti-IL1α x Anti-IL1β Bispecific Antibody (Single-chain Diabody)  (SCDB-H341)

Recombinant Anti-IL1α x Anti-IL1β Bispecific Antibody (Single-chain Diabody) is designed to be expressed as one polypeptide chain with four variable domains from two parental antibodies. The middle linker is long enough to form scFv dimers between the two diabody chains. This BsAb can block two proinflammatory cytokines simultaneously. It is designed for the research of Osteoarthritis (OA) therapy.

Specifications

Targets
IL1α & IL1β
Type
Single-chain Diabody
Species Reactivity
Human
Target 1
IL1α
Host Animal 1
Human
Target 2
IL1β
Host Animal 2
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Osteoarthritis (OA)

Targets

Target 1
IL1α
Gene ID
UniProt ID
Alternative Names
IL1; IL-1A; IL1F1; IL1-ALPHA; Interleukin 1 alpha; hematopoietin 1; IL1α
Target 2
IL1β
Gene ID
UniProt ID
Alternative Names
IL-1; IL1F2; IL1-BETA; IL1β; Interleukin-1β; IL-1β

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