Recombinant Anti-IL1α x Anti-IL1β Bispecific Antibody (scFv-Fc) (BSCFV-177)

Recombinant Anti-IL1α x Anti-IL1β Bispecific Antibody (scFv-Fc) is formed by fusing two different scFv fragments to the hinge and Fc regions, in which the Fc region are engineered by KIH. Two of scFv moiety has the antibody variable domain of either anti-IL1α specificity or anti-IL1β specificity, which produces bivalent IgG-like molecules with desired characteristics of intact antibodies. This BsAb can block two proinﬂammatory cytokines simultaneously. It is designed for the research of Osteoarthritis (OA) therapy.

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Specifications

Targets

IL1α & IL1β

Type

scFv-based Bispecific Fragments

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Osteoarthritis (OA)

Targets

Target 1

IL1α

Gene ID

3552

UniProt ID

P01583

Alternative Names

IL1; IL-1A; IL1F1; IL1-ALPHA; Interleukin 1 alpha; hematopoietin 1; IL1α

Target 2

IL1β

Gene ID

3553

UniProt ID

P01584

Alternative Names

IL-1; IL1F2; IL1-BETA; IL1β; Interleukin-1β; IL-1β

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-IL1α x Anti-IL1β Bispecific Antibody (scFv-Fc) (CAT#: BSCFV-177)

Specifications

Targets

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