Recombinant Human Anti-PDGFR1 x Human Anti-VEGF Bispecific Antibody (scFv4-Ig) (FVTIG-H349)

Recombinant Anti-PDGFR1 x Anti-VEGF Bispecific Antibody (scFv4-Ig) is an appended IgG format, which includes four scFv moieties at the N-termini of the constant regions. It is a bivalent homodimer, in which one anti-PDGFR1 scFv is fused to the CH1 domain of a heavy chain and another anti-VEGF scFv to the CL domain of a light chain, or vice versa. The resulting leads to 2+2 antigen-binding valency. This BsAb can bind two antigens simultaneously. It is designed for the research of Neovascular ocular disorders; Cancers therapy.

Datasheet INQUIRY

Specifications

Targets

PDGFR1 & VEGF

Type

Appended IgGs

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Neovascular ocular disorders; Cancers

Targets

Target 1

PDGFR1

Gene ID

5159

UniProt ID

P09619

Alternative Names

IMF1; KOGS; IBGC4; JTK12; PDGFR; PENTT; CD140B; PDGFR1; PDGFR-1; PDGFRβ; platelet-derived growth factor receptor beta; PDGFRB

Target 2

VEGF

Gene ID

7422

UniProt ID

P15692

Alternative Names

VEGFA; vascular endothelial growth factor A; VPF; VEGF; MVCD1; vascular permeability factor

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

Online Inquiry

Customer Reviews and Q&As

There are currently no customer reviews or questions for Recombinant Human Anti-PDGFR1 x Human Anti-VEGF Bispecific Antibody (scFv4-Ig) (FVTIG-H349). Click the button below to contact us or submit your feedback about this product.

Recombinant Human Anti-PDGFR1 x Human Anti-VEGF Bispecific Antibody (scFv4-Ig) (CAT#: FVTIG-H349)

Specifications

Targets

Customer Reviews and Q&As