Recombinant Anti-PDGFR1 x Anti-VEGF Bispecific Antibody (scIgG) (SCIGG-186)

Recombinant Anti-PDGFR1 x Anti-VEGF Bispecific Antibody (scIgG) is designed to be expressed as two chains, each chain has the same units with their parental IgG antibodies, anti-PDGFR1 and anti-VEGF IgGs. The two chains form heterodimer via Fc KIH technology. This BsAb can bind two antigens simultaneously. It is designed for the research of Neovascular ocular disorders; Cancers therapy.

Datasheet

Specifications

Targets

PDGFR1 & VEGF

Type

Single chain IgGs

Species Reactivity

Human

Target 1

PDGFR1

Host Animal 1

Mouse

Target 2

VEGF

Host Animal 2

Mouse

Application

FuncS; Promising therapeutic agent

Related Disease

Neovascular ocular disorders; Cancers

Targets

Target 1

PDGFR1

Gene ID

5159

UniProt ID

P09619

Alternative Names

IMF1; KOGS; IBGC4; JTK12; PDGFR; PENTT; CD140B; PDGFR1; PDGFR-1; PDGFRβ; platelet-derived growth factor receptor beta; PDGFRB

Target 2

VEGF

Gene ID

7422

UniProt ID

P15692

Alternative Names

VEGFA; vascular endothelial growth factor A; VPF; VEGF; MVCD1; vascular permeability factor

Our services and products are only for lab research, not for any diagnostic or therapeutic use.

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USA
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UK
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