Name: Anti-Human ANGPT1 Aptamer
SKU: CTMM-0124-LH54
Rating: 5 (1 reviews)

Specifications

Target Category	Protein
Target	ANGPT1
Alternative Names	ANGPT1; Angiopoietin 1; KIAA0003; AGPT-1; ANG-1; Ang1; AGP1; AGPT; ANG1; HAE5
Gene ID	284
UniProt ID	Q15389
Target Overview	This gene encodes a secreted glycoprotein that belongs to the angiopoietin family. Members of this family play important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Mutations in this gene are associated with hereditary angioedema.
Chemical Modification	2'-fluoro pyrimidines
Type	RNA
Species Reactivity	Human
Length	50-100 nt
Affinity (Kd)	1-50 nM
Binding Conditions/Buffer	20 mM HEPES, 50 mM NaCl, 2 mM CaCl_{2_{, 0.05% CHAPS, pH=7.4}}
GC Content	68.29%
Molecular Weight	12853.7 g/mole
nmoles/OD260	2.096

Anti-Human ANGPT1 Aptamer(Cat#: CTMM-0124-LH54)

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