Name: Anti-IL1B Aptamer SELEX Service
SKU: CTApt-782
Rating: 5 (1 reviews)

Certificate of Analysis Lookup

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Specifications

Target Category	Protein
Target	IL1B
Alternative Names	Interleukin 1 Beta; IL1F2; Interleukin-1 Beta; IL-1 Beta; Catabolin; IL1-BETA
Gene ID	3553
UniProt ID	P01584
Target Overview	The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.
Chemical Modification	N/A
Type	DNA
Length	20-80 nt
Affinity (Kd)	1nM~1μM
Binding Conditions/Buffer	PBS; buffer system with Serum; other

Anti-IL1B Aptamer SELEX Service(Cat#: CTApt-782)

Certificate of Analysis Lookup

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