Anti-Mouse CD279 (PD1) Aptamer(Cat#: CTMM-1024-MM4)

This product is a customized aptamer which binds to mouse CD279 (PD1) an affinity of 1-50 nM.

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Specifications
Target Category Protein
Target CD279
Alternative Names PDCD1; programmed cell death 1; PD1; PD-1; CD279; SLEB2; hPD-1; hPD-l; hSLE1; programmed cell death protein 1; protein PD-1; systemic lupus erythematosus susceptibility 2
Gene ID 5133
UniProt ID Q15116
Target Overview PD-1 is a protein encoded in humans by the PDCD1 gene. PD-1 is a cell surface receptor on T cells and B cells that has a role in regulating the immune system's response to the cells of the human body by down-regulating the immune system and promoting self-tolerance by suppressing T cell inflammatory activity. This prevents autoimmune diseases, but it can also prevent the immune system from killing cancer cells.
Type DNA
Species Reactivity Mouse
Length 20-50 nt
Affinity (Kd) <20 nM
Binding Conditions/Buffer 10 mmol/l HEPES, 150 mmol/l NaCl, 0.05% Tween-20, 1 mmol/l MgCl2, 1 mmol/l CaCl2
GC Content 63.00%
Molecular Weight 81.6
Extinction Coefficient 22964.8
nmoles/OD260 1.326
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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