This product is a customized aptamer which binds to mouse CD279 (PD1) an affinity of 1-50 nM.
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
| Target Category | Protein |
| Target | CD279 |
| Alternative Names | PDCD1; programmed cell death 1; PD1; PD-1; CD279; SLEB2; hPD-1; hPD-l; hSLE1; programmed cell death protein 1; protein PD-1; systemic lupus erythematosus susceptibility 2 |
| Gene ID | 5133 |
| UniProt ID | Q15116 |
| Target Overview | PD-1 is a protein encoded in humans by the PDCD1 gene. PD-1 is a cell surface receptor on T cells and B cells that has a role in regulating the immune system's response to the cells of the human body by down-regulating the immune system and promoting self-tolerance by suppressing T cell inflammatory activity. This prevents autoimmune diseases, but it can also prevent the immune system from killing cancer cells. |
| Type | DNA |
| Species Reactivity | Mouse |
| Length | 20-50 nt |
| Affinity (Kd) | <20 nM |
| Binding Conditions/Buffer | 10 mmol/l HEPES, 150 mmol/l NaCl, 0.05% Tween-20, 1 mmol/l MgCl2, 1 mmol/l CaCl2 |
| GC Content | 63.00% |
| Molecular Weight | 81.6 |
| Extinction Coefficient | 22964.8 |
| nmoles/OD260 | 1.326 |