Mouse Anti-Human Complement C3a/C3a desArg Monoclonal Antibody (CTJS-562)(Cat#: CTA-009)
This product is an unconjugated anti-Human Complement C3a/C3a desArg Monoclonal antibody (CTJS-562) generated from the Mouse. The antibody can be used for FC; IHC; Neut.
Summary
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Specifications
| Clonality |
Monoclonal |
| Clone |
CTJS-562 |
| Host Animal |
Mouse |
| Isotype |
IgG1κ |
| Immunogen |
Human complement component C3a |
| Species Reactivity |
Human |
| Applications |
FC; IHC; Neut |
| Application Notes |
IHC: 1:50
The optimal working dilutions should be determined by the end user. |
| Specificity |
This antibody reacts with Human complement C3a/C3a desArg. |
| Purity |
≥95% as determined by SDS-PAGE |
| Format |
Liquid |
| Size |
25 μL |
| Storage |
4°C |
| Type |
Primary Antibody |
| ProAb |
NeutAb |
Target
| Target Name |
C3a |
| Alternative Names |
Complement C3a; C3a des-Arg |
| Gene ID |
718 |
| UniProt ID |
P01024 |
Information
| Introduction |
Complement C3a is a 77 residue anaphylatoxin formed by the cleavage of complement component 3. C3a can bind to the C3a receptor induce responses. C3a is an effector of the complement system with a range of functions including T cell activation and survival, angiogenesis stimulation, chemotaxis, mast cell degranulation, and macrophage activation. C3a desArg is formed when the C-terminal arginine residue is cleaved off by serum carboxypeptidase B from C3a. C3a desArg binds to the C5L2 receptor inducing a lowered inflammatory function. |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
