Name: Recombinant Human Anti-CD19 x Human Anti-CD3 Bispecific Antibody (scFv-CH3)
SKU: BSFC-H218
Rating: 5 (1 reviews)

Recombinant Anti-CD19 x Anti-CD3 Bispecific Antibody (scFv-CH3) contains two chains. The anti-CD19 scFv is fused to the Knob-CH3 domain via a hinge region and the same as the anti-CD3 scFv to the Hole-CH3 domain, or vice versa. The KIH CH3 domains can facilitate to form a heterodimer and this bivalent binding leads to improvement in avidity. This BsAb can retarget T cells to tumor cells. It is designed for the research of B cell lymphoma; Follicular lymphoma; Leukemia therapy.

Datasheet INQUIRY

Specifications

Targets

CD19 & CD3

Type

scFv-CH3

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

B cell lymphoma; Follicular lymphoma; Leukemia

Host Animal 1

Mouse

Host Animal 2

Mouse

Targets

Target 1

CD19

Gene ID

930

UniProt ID

P15391

Alternative Names

CD19; CD19 molecule; Cluster of differentiation 19; B4; CVID3; B-lymphocyte antigen CD19; differentiation antigen CD19; T-cell surface antigen Leu-12; B-lymphocyte surface antigen B4

Target 2

CD3

Gene ID

916

UniProt ID

P07766

Alternative Names

CD3E; CD3e molecule; Cluster of differentiation 3; CD3e molecule, epsilon (CD3-TCR complex); T3E; TCRE; IMD18; T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-CD19 x Human Anti-CD3 Bispecific Antibody (scFv-CH3) (CAT#: BSFC-H218)

Specifications

Targets

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