Name: Recombinant Anti-mCD19 x Anti-mCD3 Bispecific Antibody (scFv-Fc)
SKU: KN-0125-N2
Rating: 5 (1 reviews)

Recombinant Anti-mCD19 x Anti-mCD3 Bispecific Antibody (scFv-Fc) is formed by fusing two different scFv fragments to the hinge and Fc regions, in which the Fc region are engineered by KIH. Two of scFv moiety has the antibody variable domain of either anti-mCD19 specificity or anti-mCD3 specificity, which produces bivalent IgG-like molecules with desired characteristics of intact antibodies. This BsAb can retarget T cells to tumor cells. It is designed for the research of B cell lymphoma; Follicular lymphoma; Leukemia therapy in mouse models.

Datasheet INQUIRY

Specifications

Targets

CD19 & CD3

Type

scFv-Fc

Species Reactivity

Mouse

Application

FuncS; Promising therapeutic agent

Related Disease

B cell lymphoma; Follicular lymphoma; Leukemia

Host Animal 1

Rat

Host Animal 2

Hamster

Targets

Target 1

CD19

Gene ID

12478

UniProt ID

P25918

Alternative Names

CD19; B-lymphocyte antigen CD19; B-lymphocyte surface antigen B4; Differentiation antigen CD19; Leu-12; T-cell surface antigen Leu-12

Target 2

CD3

Gene ID

12501

UniProt ID

P22646

Alternative Names

cluster of differentiation 3, T3, CD3D, CD3E, CD3G, CD3 complex, CD3Z; CD3; T3e; CD3epsilon; T-cell surface glycoprotein CD3 epsilon chain; T-cell surface antigen T3/Leu-4 epsilon chain

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-mCD19 x Anti-mCD3 Bispecific Antibody (scFv-Fc) (CAT#: KN-0125-N2)

Specifications

Targets

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