Home > Products > CD28 & FOLR1 > Recombinant Anti-CD28 x Anti-FOLR1 Bispecific Antibody (Fab-Fv)

Recombinant Anti-CD28 x Anti-FOLR1 Bispecific Antibody (Fab-Fv)  (FABFV-060)

Recombinant Anti-CD28 x Anti-FOLR1 Bispecific Antibody (Fab-Fv) is designed to be expressed as two polypeptide chains. The heavy chain Fd fragment and light chain of an anti-CD28 antibody are fused with the VL and VH domains of an anti-FOLR1 antibody respectively. It can form natural in vivo heterodimerization. This BsAb can retarget T cells to tumor cells. It is designed for the research of Ovarian cancer; Solid tumors therapy.

Specifications
Targets
CD28 & FOLR1
Type
Fab-Fv
Species Reactivity
Human
Target 1
CD28
Host Animal 1
Mouse
Target 2
FOLR1
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Ovarian cancer; Solid tumors
Targets
Target 1
CD28
Gene ID
UniProt ID
Alternative Names
CD28; CD28 molecule; Cluster of Differentiation 28; Tp44; T-cell-specific surface glycoprotein CD28; CD28 antigen
Target 2
FOLR1
Gene ID
UniProt ID
Alternative Names
FOLR1; folate receptor 1 (adult); folate receptor 1; FBP; FOLR; folate receptor alpha; FR-alpha; KB cells FBP; folate binding protein; folate receptor, adult; adult folate-binding protein; ovarian tumor-associated antigen MOv18
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