Name: Recombinant Anti-CD28 x Anti-FOLR1 Bispecific Antibody (Fab-scFv-scFv)
SKU: TRIB-060
Rating: 5 (1 reviews)

Recombinant Anti-CD28 x Anti-FOLR1 Bispecific Antibody (Fab-scFv-scFv) is designed to be expressed as two polypeptide chains respectively. The Fd fragment and LC from an anti-CD28 antibody are both extended with the scFv fragment from an anti-FOLR1 antibody. This BsAb can retarget T cells to tumor cells. It is designed for the research of Ovarian cancer; Solid tumors therapy.

Datasheet INQUIRY

Specifications

Targets

CD28 & FOLR1

Type

Fab-scFv-scFv

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Ovarian cancer; Solid tumors

Host Animal 1

Mouse

Host Animal 2

Mouse

Targets

Target 1

CD28

Gene ID

940

UniProt ID

P10747

Alternative Names

CD28; CD28 molecule; Cluster of Differentiation 28; Tp44; T-cell-specific surface glycoprotein CD28; CD28 antigen

Target 2

FOLR1

Gene ID

2348

UniProt ID

A0A024R5H1

Alternative Names

FOLR1; folate receptor 1 (adult); folate receptor 1; FBP; FOLR; folate receptor alpha; FR-alpha; KB cells FBP; folate binding protein; folate receptor, adult; adult folate-binding protein; ovarian tumor-associated antigen MOv18

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-CD28 x Anti-FOLR1 Bispecific Antibody (Fab-scFv-scFv) (CAT#: TRIB-060)

Specifications

Targets

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