Recombinant Anti-FIXa x Anti-FX Bispecific Antibody (Common light chain) (BsIgG) (KN-1022-LN5)

Recombinant Anti-FIXa x Anti-FX Bispecific Antibody (BsIgG) is designed to be expressed as three chains with Fc mutations to form heterodimers, the one common light chain overcomes the problem of heavy-chain mispairing. It has the general size and structure of a conventional IgG. This BsAb can retarget T cells to tumor cells. It is designed for the research of Multiple myeloma (MM) therapy.

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Specifications

Targets

FIXa & FX

Type

BsIgG

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Hemophilia A

Targets

Target 1

FIXa

Gene ID

2158

UniProt ID

P00740

Alternative Names

F9; coagulation factor IX; FIX; P19; PTC; HEMB; THPH8; F9 p22; FIX F9; factor 9; factor IX F9; Christmas factor; plasma thromboplastic component; plasma thromboplastin component

Target 2

Gene ID

2159

UniProt ID

P00742

Alternative Names

F10; coagulation factor X; FX; FXA; factor Xa; prothrombinase; Stuart-Prower factor

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-FIXa x Anti-FX Bispecific Antibody (Common light chain) (BsIgG) (CAT#: KN-1022-LN5)

Specifications

Targets

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