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Recombinant Anti-NGF x Anti-TNF Bispecific Antibody (scFv-CH3) (CAT#: BSFC-182)
Recombinant Anti-NGF x Anti-TNF Bispecific Antibody (scFv-CH3) contains two chains. The anti-NGF scFv is fused to the Knob-CH3 domain via a hinge region and the same as the anti-TNF scFv to the Hole-CH3 domain, or vice versa. The KIH CH3 domains can facilitate to form a heterodimer and this bivalent binding leads to improvement in avidity. This BsAb can bind and inactivate two ligands simultaneously. It is designed for the research of Osteoarthritis therapy.
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