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NGF & TNF Bispecific Antibodies
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CAT# Product Name Species Reactivity BsAb Type Target 1 Host Animal 1 Target 2 Host Animal 2 INQUIRY
T-BSDB-H344 Recombinant Human Anti-NGF x Human Anti-TNF Bispecific Antibody (Tandem Diabody) Human Tandem Diabody NGF Human TNF Human Inquiry
T-BSDB-182 Recombinant Anti-NGF x Anti-TNF Bispecific Antibody (Tandem Diabody) Human Tandem Diabody NGF Mouse TNF Mouse Inquiry
SCIGG-H346 Recombinant Human Anti-NGF x Human Anti-TNF Bispecific Antibody (scIgG) Human Single chain IgGs NGF Human TNF Human Inquiry
SCIGG-182 Recombinant Anti-NGF x Anti-TNF Bispecific Antibody (scIgG) Human Single chain IgGs NGF Mouse TNF Mouse Inquiry
FVTIG-H346 Recombinant Human Anti-NGF x Human Anti-TNF Bispecific Antibody (scFv4-Ig) Human scFv4-Ig NGF Human TNF Human Inquiry
FVTIG-182 Recombinant Anti-NGF x Anti-TNF Bispecific Antibody (scFv4-Ig) Human scFv4-Ig NGF Mouse TNF Mouse Inquiry
BSSG-H346 Recombinant Human Anti-NGF x Human Anti-TNF Bispecific Antibody (scFv-IgG) Human scFv-IgG NGF Human TNF Human Inquiry
BSSG-182 Recombinant Anti-NGF x Anti-TNF Bispecific Antibody (scFv-IgG) Human scFv-IgG NGF Mouse TNF Mouse Inquiry
IGLFV-H346 Recombinant Human Anti-NGF x Human Anti-TNF Bispecific Antibody (IgG(L)-scFv) Human IgG-scFv NGF Human TNF Human Inquiry
IGLFV-182 Recombinant Anti-NGF x Anti-TNF Bispecific Antibody (IgG(L)-scFv) Human IgG-scFv NGF Mouse TNF Mouse Inquiry
BSGV-H346 Recombinant Human Anti-NGF x Human Anti-TNF Bispecific Antibody (IgG-Fv) Human IgG-Fv NGF Mouse TNF Mouse Inquiry
BSGV-182 Recombinant Anti-NGF x Anti-TNF Bispecific Antibody (IgG-Fv) Human IgG-Fv NGF Mouse TNF Mouse Inquiry
BSDG-H346 Recombinant Human Anti-NGF x Human Anti-TNF Bispecific Antibody (Fv-IgG) Human Fv-IgG NGF Human TNF Human Inquiry
BSDG-182 Recombinant Anti-NGF x Anti-TNF Bispecific Antibody (Fv-IgG) Human Fv-IgG NGF Mouse TNF Mouse Inquiry
BABFV-H346 Recombinant Human Anti-NGF x Human Anti-TNF Bispecific Antibody (F(ab')2-scFv2) Human F(ab')2-scFv2 NGF Human TNF Human Inquiry
BABFV-182 Recombinant Anti-NGF x Anti-TNF Bispecific Antibody (F(ab')2-scFv2) Human F(ab')2-scFv2 NGF Mouse TNF Mouse Inquiry
FABVC-H346 Recombinant Human Anti-NGF x Human Anti-TNF Bispecific Antibody (Fab-scFv-Fc) Human Fab-scFv/sdAb-Fc NGF Human TNF Human Inquiry
FABVC-182 Recombinant Anti-NGF x Anti-TNF Bispecific Antibody (Fab-scFv-Fc) Human Fab-scFv/sdAb-Fc NGF Mouse TNF Mouse Inquiry
SCDBC-H346 Recombinant Human Anti-NGF x Human Anti-TNF Bispecific Antibody (scDiabody-CH3) Human scDiabody-CH3 NGF Human TNF Human Inquiry
SCDBC-182 Recombinant Anti-NGF x Anti-TNF Bispecific Antibody (scDiabody-CH3) Human scDiabody-CH3 NGF Mouse TNF Mouse Inquiry
BSDBC-H346 Recombinant Human Anti-NGF x Human Anti-TNF Bispecific Antibody (Diabody-CH3) Human Diabody-CH3 NGF Human TNF Human Inquiry
BSDBC-182 Recombinant Anti-NGF x Anti-TNF Bispecific Antibody (Diabody-CH3) Human Diabody-CH3 NGF Mouse TNF Mouse Inquiry
SCDBF-H346 Recombinant Human Anti-NGF x Human Anti-TNF Bispecific Antibody (scDiabody-Fc) Human scDiabody-Fc NGF Human TNF Human Inquiry
SCDBF-182 Recombinant Anti-NGF x Anti-TNF Bispecific Antibody (scDiabody-Fc) Human scDiabody-Fc NGF Mouse TNF Mouse Inquiry
BSFVF-H346 Recombinant Human Anti-NGF x Human Anti-TNF Bispecific Antibody (Tandem scFv-Fc) Human Tandem scFv-Fc NGF Human TNF Human Inquiry
BSFVF-182 Recombinant Anti-NGF x Anti-TNF Bispecific Antibody (Tandem scFv-Fc) Human Tandem scFv-Fc NGF Mouse TNF Mouse Inquiry
BSDBF-H346 Recombinant Human Anti-NGF x Human Anti-TNF Bispecific Antibody (Diabody-Fc) Human Diabody-Fc NGF Human TNF Human Inquiry
BSDBF-182 Recombinant Anti-NGF x Anti-TNF Bispecific Antibody (Diabody-Fc) Human Diabody-Fc NGF Mouse TNF Mouse Inquiry
BSTF-H346 Recombinant Human Anti-NGF x Human Anti-TNF Bispecific Antibody (scFv-Fc-scFv) Human scFv-Fc-scFv NGF Mouse TNF Mouse Inquiry
BSTF-182 Recombinant Anti-NGF x Anti-TNF Bispecific Antibody (scFv-Fc-scFv) Human scFv-Fc-scFv NGF Mouse TNF Mouse Inquiry
BSCFV-H346 Recombinant Human Anti-NGF x Human Anti-TNF Bispecific Antibody (scFv-Fc) Human scFv-Fc NGF Mouse TNF Mouse Inquiry
BSCFV-182 Recombinant Anti-NGF x Anti-TNF Bispecific Antibody (scFv-Fc) Human scFv-Fc NGF Mouse TNF Mouse Inquiry
MNAB-H346 Recombinant Human Anti-NGF x Human Anti-TNF Bispecific Antibody (Miniantibody) Human Miniantibody NGF Mouse TNF Mouse Inquiry
MNAB-182 Recombinant Anti-NGF x Anti-TNF Bispecific Antibody (Miniantibody) Human Miniantibody NGF Mouse TNF Mouse Inquiry
BSFC-H346 Recombinant Human Anti-NGF x Human Anti-TNF Bispecific Antibody (scFv-CH3) Human scFv-CH3 NGF Mouse TNF Mouse Inquiry
BSFC-182 Recombinant Anti-NGF x Anti-TNF Bispecific Antibody (scFv-CH3) Human scFv-CH3 NGF Mouse TNF Mouse Inquiry
BSCC-H346 Recombinant Human Anti-NGF x Human Anti-TNF Bispecific Antibody (scFv-CH1/CL) Human scFv-CH1/CL NGF Mouse TNF Mouse Inquiry
BSCC-182 Recombinant Anti-NGF x Anti-TNF Bispecific Antibody (scFv-CH1/CL) Human scFv-CH1/CL NGF Mouse TNF Mouse Inquiry
BIBD-H346 Recombinant Human Anti-NGF x Human Anti-TNF Bispecific Antibody (Bibody) Human Bibody NGF Mouse TNF Mouse Inquiry
BIBD-182 Recombinant Anti-NGF x Anti-TNF Bispecific Antibody (Bibody) Human Bibody NGF Mouse TNF Mouse Inquiry
FABFV-H346 Recombinant Human Anti-NGF x Human Anti-TNF Bispecific Antibody (Fab-Fv) Human Fab-Fv NGF Human TNF Human Inquiry
FABFV-182 Recombinant Anti-NGF x Anti-TNF Bispecific Antibody (Fab-Fv) Human Fab-Fv NGF Mouse TNF Mouse Inquiry
MiniB-H346 Recombinant Human Anti-NGF x Human Anti-TNF Bispecific Antibody (Minibody) Human Minibody NGF Human TNF Human Inquiry
MiniB-182 Recombinant Anti-NGF x Anti-TNF Bispecific Antibody (Minibody) Human Minibody NGF Mouse TNF Mouse Inquiry
SCDB-H344 Recombinant Human Anti-NGF x Anti-TNF Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody NGF Human TNF Human Inquiry
FABIG-H344 Recombinant Human Anti-NGF x Anti-TNF Bispecific Antibody (Fab-IgG) Human Fab-IgG NGF Human TNF Human Inquiry
TRIB-H346 Recombinant Human Anti-NGF x Anti-TNF Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv NGF Human TNF Human Inquiry
BSIG-H344 Human Anti-NGF x Anti-TNF Bispecific Antibody (IgG-IgG) Human IgG-IgG NGF Human TNF Human Inquiry
CROSSAB-H344 Recombinant Human Anti-NGF x Anti-TNF Bispecific Antibody (CrossMab) Human CrossMab NGF Human TNF Human Inquiry
IGFV-H344 Recombinant Human Anti-NGF x Anti-TNF Bispecific Antibody (IgG-scFv) Human IgG-scFv NGF Human TNF Human Inquiry
BSDB-H344 Recombinant Human Anti-NGF x Anti-TNF Bispecific Antibody (Diabody) Human Diabody NGF Human TNF Human Inquiry
BSFAB-H344 Recombinant Human Anti-NGF x Anti-TNF Bispecific Antibody (Tandem Fab) Human Tandem Fab NGF Human TNF Human Inquiry
BSFV-H343 Recombinant Human Anti-NGF x Anti-TNF Bispecific Antibody (Tandem scFv) Human Tandem scFv NGF Human TNF Human Inquiry
SCDB-182 Recombinant Anti-NGF x Anti-TNF Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody NGF Mouse TNF Mouse Inquiry
FABIG-182 Recombinant Anti-NGF x Anti-TNF Bispecific Antibody (Fab-IgG) Human Fab-IgG NGF Mouse TNF Mouse Inquiry
TRIB-182 Recombinant Anti-NGF x Anti-TNF Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv NGF Mouse TNF Mouse Inquiry
BSIG-182 Anti-NGF x Anti-TNF Bispecific Antibody (IgG-IgG) Human IgG-IgG NGF Mouse TNF Mouse Inquiry
IGFV-182 Recombinant Anti-NGF x Anti-TNF Bispecific Antibody (IgG-scFv) Human IgG-scFv NGF Mouse TNF Mouse Inquiry
BSDB-182 Recombinant Anti-NGF x Anti-TNF Bispecific Antibody (Diabody) Human Diabody NGF Mouse TNF Mouse Inquiry
BSFAB-182 Recombinant Anti-NGF x Anti-TNF Bispecific Antibody (Tandem Fab) Human Tandem Fab NGF Mouse TNF Mouse Inquiry
BSFV-182 Recombinant Anti-NGF x Anti-TNF Bispecific Antibody (Tandem scFv) Human Tandem scFv NGF Mouse TNF Mouse Inquiry
BSTF-H340 Recombinant Human Anti-IL17 x Human Anti-TNF Bispecific Antibody (scFv-Fc-scFv) Human scFv-Fc-scFv IL17 Mouse TNF Mouse Inquiry
BSTF-H195 Recombinant Human Anti-albumin x Human Anti-TNF Bispecific Antibody (scFv-Fc-scFv) Human scFv-Fc-scFv albumin Mouse TNF Mouse Inquiry
BSTF-175 Recombinant Anti-IL17 x Anti-TNF Bispecific Antibody (scFv-Fc-scFv) Human scFv-Fc-scFv IL17 Mouse TNF Mouse Inquiry
BSTF-007 Recombinant Anti-albumin x Anti-TNF Bispecific Antibody (scFv-Fc-scFv) Human scFv-Fc-scFv albumin Mouse TNF Mouse Inquiry
BSCFV-H340 Recombinant Human Anti-IL17 x Human Anti-TNF Bispecific Antibody (scFv-Fc) Human scFv-Fc IL17 Mouse TNF Mouse Inquiry
BSCFV-H195 Recombinant Human Anti-albumin x Human Anti-TNF Bispecific Antibody (scFv-Fc) Human scFv-Fc albumin Mouse TNF Mouse Inquiry
BSCFV-175 Recombinant Anti-IL17 x Anti-TNF Bispecific Antibody (scFv-Fc) Human scFv-Fc IL17 Mouse TNF Mouse Inquiry
BSCFV-007 Recombinant Anti-albumin x Anti-TNF Bispecific Antibody (scFv-Fc) Human scFv-Fc albumin Mouse TNF Mouse Inquiry
MNAB-H340 Recombinant Human Anti-IL17 x Human Anti-TNF Bispecific Antibody (Miniantibody) Human Miniantibody IL17 Mouse TNF Mouse Inquiry
MNAB-H195 Recombinant Human Anti-albumin x Human Anti-TNF Bispecific Antibody (Miniantibody) Human Miniantibody albumin Mouse TNF Mouse Inquiry
MNAB-175 Recombinant Anti-IL17 x Anti-TNF Bispecific Antibody (Miniantibody) Human Miniantibody IL17 Mouse TNF Mouse Inquiry
MNAB-007 Recombinant Anti-albumin x Anti-TNF Bispecific Antibody (Miniantibody) Human Miniantibody albumin Mouse TNF Mouse Inquiry
BSFC-H340 Recombinant Human Anti-IL17 x Human Anti-TNF Bispecific Antibody (scFv-CH3) Human scFv-CH3 IL17 Mouse TNF Mouse Inquiry
BSFC-H195 Recombinant Human Anti-albumin x Human Anti-TNF Bispecific Antibody (scFv-CH3) Human scFv-CH3 albumin Mouse TNF Mouse Inquiry
BSFC-175 Recombinant Anti-IL17 x Anti-TNF Bispecific Antibody (scFv-CH3) Human scFv-CH3 IL17 Mouse TNF Mouse Inquiry
BSFC-007 Recombinant Anti-albumin x Anti-TNF Bispecific Antibody (scFv-CH3) Human scFv-CH3 albumin Mouse TNF Mouse Inquiry
BSCC-H340 Recombinant Human Anti-IL17 x Human Anti-TNF Bispecific Antibody (scFv-CH1/CL) Human scFv-CH1/CL IL17 Mouse TNF Mouse Inquiry
BSCC-H195 Recombinant Human Anti-albumin x Human Anti-TNF Bispecific Antibody (scFv-CH1/CL) Human scFv-CH1/CL albumin Mouse TNF Mouse Inquiry
BSCC-175 Recombinant Anti-IL17 x Anti-TNF Bispecific Antibody (scFv-CH1/CL) Human scFv-CH1/CL IL17 Mouse TNF Mouse Inquiry
BSCC-007 Recombinant Anti-albumin x Anti-TNF Bispecific Antibody (scFv-CH1/CL) Human scFv-CH1/CL albumin Mouse TNF Mouse Inquiry
BIBD-H340 Recombinant Human Anti-IL17 x Human Anti-TNF Bispecific Antibody (Bibody) Human Bibody IL17 Mouse TNF Mouse Inquiry
BIBD-H195 Recombinant Human Anti-Albumin x Human Anti-TNF Bispecific Antibody (Bibody) Human Bibody Albumin Mouse TNF Mouse Inquiry
BIBD-175 Recombinant Anti-IL17 x Anti-TNF Bispecific Antibody (Bibody) Human Bibody IL17 Mouse TNF Mouse Inquiry
BIBD-007 Recombinant Anti-Albumin x Anti-TNF Bispecific Antibody (Bibody) Human Bibody Albumin Mouse TNF Mouse Inquiry
FABFV-H340 Recombinant Human Anti-IL17 x Human Anti-TNF Bispecific Antibody (Fab-Fv) Human Fab-Fv IL17 Human TNF Human Inquiry
FABFV-H195 Recombinant Human Anti-Albumin x Human Anti-TNF Bispecific Antibody (Fab-Fv) Human Fab-Fv Albumin Human TNF Human Inquiry
FABFV-175 Recombinant Anti-IL17 x Anti-TNF Bispecific Antibody (Fab-Fv) Human Fab-Fv IL17 Mouse TNF Mouse Inquiry
FABFV-007 Recombinant Anti-Albumin x Anti-TNF Bispecific Antibody (Fab-Fv) Human Fab-Fv Albumin Mouse TNF Mouse Inquiry
MiniB-H340 Recombinant Human Anti-IL17 x Human Anti-TNF Bispecific Antibody (Minibody) Human Minibody IL17 Human TNF Human Inquiry
MiniB-H195 Recombinant Human Anti-Albumin x Human Anti-TNF Bispecific Antibody (Minibody) Human Minibody Albumin Human TNF Human Inquiry
MiniB-175 Recombinant Anti-IL17 x Anti-TNF Bispecific Antibody (Minibody) Human Minibody IL17 Mouse TNF Mouse Inquiry
MiniB-007 Recombinant Anti-Albumin x Anti-TNF Bispecific Antibody (Minibody) Human Minibody Albumin Mouse TNF Mouse Inquiry
SCDB-H339 Recombinant Human Anti-IL17 x Anti-TNF Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody IL17 Human TNF Human Inquiry
SCDB-H193 Recombinant Human Anti-Albumin x Anti-TNF Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody Albumin Human TNF Human Inquiry
FABIG-H339 Recombinant Human Anti-IL17 x Anti-TNF Bispecific Antibody (Fab-IgG) Human Fab-IgG IL17 Human TNF Human Inquiry
FABIG-H193 Recombinant Human Anti-Albumin x Anti-TNF Bispecific Antibody (Fab-IgG) Human Fab-IgG Albumin Human TNF Human Inquiry
TRIB-H341 Recombinant Human Anti-IL17 x Anti-TNF Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv IL17 Human TNF Human Inquiry
TRIB-H195 Recombinant Human Anti-Albumin x Anti-TNF Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv Albumin Human TNF Human Inquiry
BSIG-H339 Human Anti-IL17 x Anti-TNF Bispecific Antibody (IgG-IgG) Human IgG-IgG IL17 Human TNF Human Inquiry
BSIG-H193 Human Anti-Albumin x Anti-TNF Bispecific Antibody (IgG-IgG) Human IgG-IgG Albumin Human TNF Human Inquiry
CROSSAB-H339 Recombinant Human Anti-IL17 x Anti-TNF Bispecific Antibody (CrossMab) Human CrossMab IL17 Human TNF Human Inquiry
CROSSAB-H193 Recombinant Human Anti-Albumin x Anti-TNF Bispecific Antibody (CrossMab) Human CrossMab Albumin Human TNF Human Inquiry
IGFV-H339 Recombinant Human Anti-IL17 x Anti-TNF Bispecific Antibody (IgG-scFv) Human IgG-scFv IL17 Human TNF Human Inquiry
IGFV-H193 Recombinant Human Anti-Albumin x Anti-TNF Bispecific Antibody (IgG-scFv) Human IgG-scFv Albumin Human TNF Human Inquiry
BSDB-H339 Recombinant Human Anti-IL17 x Anti-TNF Bispecific Antibody (Diabody) Human Diabody IL17 Human TNF Human Inquiry
BSDB-H193 Recombinant Human Anti-Albumin x Anti-TNF Bispecific Antibody (Diabody) Human Diabody Albumin Human TNF Human Inquiry
BSFAB-H339 Recombinant Human Anti-IL17 x Anti-TNF Bispecific Antibody (Tandem Fab) Human Tandem Fab IL17 Human TNF Human Inquiry
BSFAB-H193 Recombinant Human Anti-Albumin x Anti-TNF Bispecific Antibody (Tandem Fab) Human Tandem Fab Albumin Human TNF Human Inquiry
BSFV-H337 Recombinant Human Anti-IL17 x Anti-TNF Bispecific Antibody (Tandem scFv) Human Tandem scFv IL17 Human TNF Human Inquiry
BSFV-H193 Recombinant Human Anti-Albumin x Anti-TNF Bispecific Antibody (Tandem scFv) Human Tandem scFv Albumin Human TNF Human Inquiry
SCDB-175 Recombinant Anti-IL17 x Anti-TNF Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody IL17 Mouse TNF Mouse Inquiry
SCDB-007 Recombinant Anti-Albumin x Anti-TNF Bispecific Antibody (Single-chain Diabody) Human Single-chain Diabody Albumin Mouse TNF Mouse Inquiry
FABIG-175 Recombinant Anti-IL17 x Anti-TNF Bispecific Antibody (Fab-IgG) Human Fab-IgG IL17 Mouse TNF Mouse Inquiry
FABIG-007 Recombinant Anti-Albumin x Anti-TNF Bispecific Antibody (Fab-IgG) Human Fab-IgG Albumin Mouse TNF Mouse Inquiry
TRIB-175 Recombinant Anti-IL17 x Anti-TNF Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv IL17 Mouse TNF Mouse Inquiry
TRIB-007 Recombinant Anti-Albumin x Anti-TNF Bispecific Antibody (Fab-scFv-scFv) Human Fab-scFv-scFv Albumin Mouse TNF Mouse Inquiry
BSIG-175 Anti-IL17 x Anti-TNF Bispecific Antibody (IgG-IgG) Human IgG-IgG IL17 Mouse TNF Mouse Inquiry
BSIG-007 Anti-Albumin x Anti-TNF Bispecific Antibody (IgG-IgG) Human IgG-IgG Albumin Mouse TNF Mouse Inquiry
CROSSAB-175 Recombinant Anti-IL17 x Anti-TNF Bispecific Antibody (CrossMab) Human CrossMab IL17 Mouse TNF Mouse Inquiry
CROSSAB-007 Recombinant Anti-Albumin x Anti-TNF Bispecific Antibody (CrossMab) Human CrossMab Albumin Mouse TNF Mouse Inquiry
IGFV-175 Recombinant Anti-IL17 x Anti-TNF Bispecific Antibody (IgG-scFv) Human IgG-scFv IL17 Mouse TNF Mouse Inquiry
IGFV-007 Recombinant Anti-Albumin x Anti-TNF Bispecific Antibody (IgG-scFv) Human IgG-scFv Albumin Mouse TNF Mouse Inquiry
BSDB-175 Recombinant Anti-IL17 x Anti-TNF Bispecific Antibody (Diabody) Human Diabody IL17 Mouse TNF Mouse Inquiry
BSDB-007 Recombinant Anti-Albumin x Anti-TNF Bispecific Antibody (Diabody) Human Diabody Albumin Mouse TNF Mouse Inquiry
BSFAB-175 Recombinant Anti-IL17 x Anti-TNF Bispecific Antibody (Tandem Fab) Human Tandem Fab IL17 Mouse TNF Mouse Inquiry
BSFAB-007 Recombinant Anti-Albumin x Anti-TNF Bispecific Antibody (Tandem Fab) Human Tandem Fab Albumin Mouse TNF Mouse Inquiry
BSFV-175 Recombinant Anti-IL17 x Anti-TNF Bispecific Antibody (Tandem scFv) Human Tandem scFv IL17 Mouse TNF Mouse Inquiry
BSFV-007 Recombinant Anti-Albumin x Anti-TNF Bispecific Antibody (Tandem scFv) Human Tandem scFv Albumin Mouse TNF Mouse Inquiry

Background

Tumor Necrosis Factor-alpha (TNF-α) constitutes a multifunctional pro-inflammatory cytokine, primarily synthesized in monocytic and macrophage cells. TNF-α functions within the immune system, where its activation invariably amplifies immunological responses and instigates inflammatory actions.

Meanwhile, the Nerve Growth Factor (NGF) fosters organogenesis by propagating the growth of endocrine or immune system-influenced sympathetic neurons, peripheral sensory neurons, and vasculature. Additionally, NGF plays an integral role in the regulation of insulin secretion, lipolysis, and maintenance of metabolic balance.

Historically, the disparate roles of TNF-α and NGF across varying systems have been examined independently. However, accumulating evidence suggests that NGF holds the capacity to modulate inflammatory phenotypes and cytokine secretion, thereby participating in immune system functionality through a crosstalk mechanism with TNF-α. This interface is postulated to be strongly associated with the pathogenesis of various diseases including asthma, lung cancer, and allergies among others.

Signaling pathways of NGF and TNF-α. (Takei, et al., 208) Fig.1 NGF and TNF-α signaling.1

Reference

  1. Takei, Laskey, et al. " Interpreting crosstalk between TNF-α and NGF: potential implications for disease." Trends in Molecular Medicine. 14.9 (2008): 381.
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