Name: Recombinant Anti-CEA x Anti-GD2 Tandem Fab-NGB immunotoxin (Bispecific Immunotoxin)
SKU: BSFAB-NGB005
Rating: 5 (1 reviews)

Recombinant Anti-CEA x Anti-GD2 Tandem Fab-NGB immunotoxin (Bispecific Immunotoxin) is designed to be expressed as the Nigrin b (NGB) fused to a tandem Fab recognizing CEA and GD2. It contains three chains and a His-tag at the C/N terminus for affinity purification. The two Fd regions are connected by a flexible linker. This bispecific immunotoxin can deliver NGB to antigen-specific cells. Then NGB is a lectin and can kill the target cells. The bispecific immunotoxin is designed for the research of Neuroblastoma; Osteosarcoma; Melanoma; Solid tumors therapy.

Datasheet INQUIRY

Specifications

Targets

CEA & GD2

Type

Bispecific Immunotoxin

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Neuroblastoma; Osteosarcoma; Melanoma; Solid tumors

Targets

Target 1

CEA

Gene ID

1048

UniProt ID

A0A024R0K5

Alternative Names

CEACAM5; carcinoembryonic antigen; carcinoembryonic antigen related cell adhesion molecule 5; CEA; CD66e; meconium antigen 100

Target 2

GD2

Alternative Names

Ganglioside GD2; GD2; Ganglioside; Disialoganglioside GD2

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-CEA x Anti-GD2 Tandem Fab-NGB immunotoxin (Bispecific Immunotoxin) (CAT#: BSFAB-NGB005)

Specifications

Targets

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