Anti-ANGPT2 Aptamer SELEX Service(Cat#: CTApt-696)

This is an aptamer development services to screening aptamers binds to the ANGPT2 with an affinity of 1nM~1μM.

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Specifications
Target Category Protein
Target ANGPT2
Alternative Names Angiopoietin 2; Angiopoietin-2; ANG-2; Angiopoietin-2B; Angiopoietin-2a; Tie2-Ligand; ANGPT2; AGPT2; ANG2; Ang2
Gene ID 285
UniProt ID O15123
Target Overview This gene belongs to the angiopoietin family of growth factors. The protein encoded by this gene is an antagonist of angiopoietin 1, and both angiopoietin 1 and angiopoietin 2 are ligands for the endothelial TEK receptor tyrosine kinase. Angiopoietin 2 is upregulated in multiple inflammatory diseases and is implicated in the direct control of inflammation-related signaling pathways. The encoded protein affects angiogenesis during embryogenesis and tumorigenesis, disrupts the vascular remodeling ability of angiopoietin 1, and may induce endothelial cell apoptosis. This gene serves a prognostic biomarker for acute respiratory distress syndrome.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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