Anti-Human ANGPT2 Aptamer(Cat#: CTMM-0124-LH1)

This product is an aptamer which binds to Human ANGPT2 domain with a high affinity.

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Specifications
Target Category Protein
Target ANGPT2
Alternative Names Angiopoietin 2; Ang2; Angiopoietin-2B; Angiopoietin-2a; Tie2-Ligand; LMPHM10; AGPT2; ANG-2; ANG2
Gene ID 285
UniProt ID O15123
Target Overview This gene belongs to the angiopoietin family of growth factors. The protein encoded by this gene is an antagonist of angiopoietin 1, and both angiopoietin 1 and angiopoietin 2 are ligands for the endothelial TEK receptor tyrosine kinase. Angiopoietin 2 is upregulated in multiple inflammatory diseases and is implicated in the direct control of inflammation-related signaling pathways. The encoded protein affects angiogenesis during embryogenesis and tumorigenesis, disrupts the vascular remodeling ability of angiopoietin 1, and may induce endothelial cell apoptosis. This gene serves a prognostic biomarker for acute respiratory distress syndrome.
Type RNA
Species Reactivity Human
Length <50 nt
Binding Conditions/Buffer Tris buffered saline (TBS), pH=7.4
GC Content 58.14%
Molecular Weight 13231.8 g/mole
nmoles/OD260 2.125

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